The theme of the February SUSS Journal Club is Neurosurgery/Neuro-Oncology.
Glioblastomas are the most common primary malignant brain tumour in the adult population and the prognosis is currently very poor – with median survival from diagnosis often reported at under 12 months. This month we have two papers discussing the treatment of glioblastomas.
Konrad Schultz (stage 3 SMP student) will present a trial considering glioblastoma treatments. Traditionally, standard therapy consists of surgical resection, followed by radiotherapy. The article considers the efficacy and safety of either radiotherapy alone, radiotherapy plus temozolomide (a chemotherapeutic agent) – given concomitantly with and after radiotherapy.
Vijidha Rajkumar (stage 2 SMP student) is presenting an article focusing on the benefits of aggressive surgical resection for glioblastoma patient survival. Maximizing the extent of resection of tumours has been shown to improve survival in patients with GBM. This paper considers a number of tumour factors and the benefits of maximizing the extent of surgical resection.
Date: Monday, February 26th, 2018
Time: 6:00 – 7:00 pm
Venue: RPAH Institute of Academic Surgery
Stupp, Roger, et al. “Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.” New England Journal of Medicine 352.10 (2005): 987-996.
Awad, Al-Wala, et al. “Impact of removed tumor volume and location on patient outcome in glioblastoma.” Journal of neuro-oncology 135.1 (2017): 161-171.
Hope you see you there!